We both came to supplements the same way most people do: recommendation, label appeal, a brand that looked credible. We tried magnesium for rest. Ashwagandha for stress. Lion’s Mane for focus.
Some things worked. Most didn’t. And when we started looking at why, the pattern was always the same: the dose on the label was not the dose in the research.
Magnesium oxide at 400mg looks like a serious supplement. But at 4% bioavailability, you are absorbing around 16mg of elemental magnesium. The trial showing rest improvement used 275mg absorbed. You would need to take 17 of those capsules to reach it.
Lion’s Mane at 1,000mg looks impressive too. Until you find out most products use mycelium grown on grain substrate, and the final powder is 50 to 70% oat starch. The hericenone compounds that stimulate NGF synthesis are in the fruiting body, not the grain.
This was not obscure information. It was in the published literature. Freely available. The brands knew. They just did not think customers would check. We checked. Then we got angry. Then we started building.