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Our story

Built on one frustration.

Every supplement we tried was either dosed wrong, made with inferior forms, or packaged like a protein shake. We decided to fix it properly.

9
Active SKUs across REST · RISE · RENEW
GMP
21 CFR Part 111 certified US manufacturing
COA
Third-party tested, every single batch
0
Proprietary blends. Every dose on the label.

01 · THE PROBLEM

The dose on the label was not the dose in the research.

We both came to supplements the same way most people do: recommendation, label appeal, a brand that looked credible. We tried magnesium for rest. Ashwagandha for stress. Lion’s Mane for focus.

Some things worked. Most didn’t. And when we started looking at why, the pattern was always the same: the dose on the label was not the dose in the research.

Magnesium oxide at 400mg looks like a serious supplement. But at 4% bioavailability, you are absorbing around 16mg of elemental magnesium. The trial showing rest improvement used 275mg absorbed. You would need to take 17 of those capsules to reach it.

Lion’s Mane at 1,000mg looks impressive too. Until you find out most products use mycelium grown on grain substrate, and the final powder is 50 to 70% oat starch. The hericenone compounds that stimulate NGF synthesis are in the fruiting body, not the grain.

This was not obscure information. It was in the published literature. Freely available. The brands knew. They just did not think customers would check. We checked. Then we got angry. Then we started building.

The supplement industry does not have a quality problem. It has an honesty problem. Most brands are counting on you not knowing the difference.

AE·ORA, founding principle

What we kept finding

  • Sub-therapeutic doses hidden behind impressive label numbers
  • Inferior molecular forms chosen for cost, not efficacy
  • Proprietary blends obscuring individual ingredient amounts
  • Marketing copy citing studies that used different forms or doses
  • Mycelium-on-grain products sold as Lion’s Mane with no fruiting body
  • Magnesium oxide positioned as premium because the label dose looked high
  • Products targeting the same biological pathway twice, wasting the budget
  • Brands adding ingredients at sub-therapeutic doses to fill out the label

02 · THE DECISION

One constraint. Everything follows.

AE·ORA founder at research desk

We set a single rule before we designed a single capsule: every dose must match the trial that validated it. Not approximately. Not inspired by. The exact figure used in the published research.

That constraint eliminated most of the supplement market immediately. If we could not dose it correctly, we would not include it. If the form used in our product had not been tested in the trial, we would use the form that had been. If we could not verify batch purity at third-party standard, we would not sell it.

It also meant AE·ORA would launch with a focused range, not forty SKUs. That was a deliberate choice. Nine things dosed properly will always outperform forty things dosed wrong.

THE SINGLE CONSTRAINT

Every dose must match the trial that validated it. Not approximately. Not “inspired by.” The exact figure used in the published randomised controlled trial. If we cannot dose it correctly, it does not go in the product.

  1. The frustration becomes a project

    Months of literature review

    Every ingredient evaluated against its primary research. Forms, doses, bioavailability, mechanism. The brief: build the supplement we wish existed. No ingredient makes it in without a peer-reviewed RCT at the dose and form we intend to use.

  2. The range

    REST · RISE · RENEW — three systems, one loop

    REST for the nightly recovery window. RISE for the morning performance system. RENEW for the cellular foundation underneath both. Nine SKUs. Every ingredient at the dose that validates it.

  3. The standard

    Third-party testing protocol established

    Every batch tested at an independent laboratory before release. Identity, potency, heavy metals, microbial. COA on file. Non-negotiable from batch one.

  4. AE·ORA

    REST · RISE · RENEW. Close the loop.

    The brand that starts with the research. Three systems. One loop. No proprietary blends. Every dose on the label. Every time.

03 · WHAT WE BUILT ON

Three rules we do not break.

Every decision across formulation, sourcing, testing, and marketing runs through these three questions.

RULE 01

The dose matches the trial. Exactly.

If the RCT used 275mg elemental magnesium glycinate, that is what goes in the capsule. Not 250mg because it is cheaper. Not 400mg to look impressive on the label. The number in the study is the number we use. If we cannot dose it correctly, it does not go in the product.

RULE 02

The form used in the research is the form we use.

KSM-66 is standardised to 5% withanolides — the exact specification used in the Chandrasekhar et al. trial. Lion’s Mane is dual-extracted fruiting body, the form used in the Mori et al. RCT. We do not substitute cheaper forms and cite studies that used better ones.

RULE 03

Every batch verified at an independent laboratory.

Not internal QC. Not the manufacturer’s testing. An independent third-party laboratory, every batch, before any unit ships. Not spot checks, not quarterly audits. Every batch. COA on file and available on request. This is not a selling point. It is a baseline.

04 · THE FORMULAS

Three systems. One loop.

REST, RISE, and RENEW are built around distinct biological pathways. No overlap. No ingredient does double duty. Each one earns its place or it is not there.

REST

The nightly system. Zero melatonin.

REST addresses the cortisol-melatonin handoff that most rest products ignore entirely. Melatonin suppresses your own production over time. REST works upstream — supporting the nervous system conditions that allow genuine rest to happen.

Magnesium Glycinate
275mg elemental · 90 capsules
Elemental magnesium at the exact dose used in the rest-quality RCT. Glycinate form for high bioavailability and the calming glycine co-factor. Activates parasympathetic tone in the cortisol-to-melatonin handoff window.
Ashwagandha Capsules
500mg/day · 60 capsules
Standardised root extract dosed to the cortisol-reduction trial. Modulates the HPA axis to lower evening cortisol — the upstream condition that keeps people awake at 3am.
Reishi Relax Gummies
200mg Reishi · 30 gummies
Dual-extracted Reishi fruiting body for triterpene + beta-glucan content. Adaptogenic support for the wind-down window without sedation or melatonin dependency.

RISE

The morning performance system.

RISE opens the day with what REST rebuilt overnight. The cognitive and physical performance stack — NGF synthesis, adaptogenic stamina, and acute focus support — all without caffeine dependency.

Lion’s Mane Mushroom Capsules
1000mg total · 400mg active
Hericenones in the fruiting body and erinacines in the mycelium stimulate Nerve Growth Factor synthesis. Dual-extracted, fruiting-body-led — the form used in the Mori et al. cognition RCT, not the cheap mycelium-on-grain substrate most brands ship.
Mushroom Energy & Cognition Drops
100mg Cordyceps · 25mg Alpha GPC
Liquid delivery for fast onset. Cordyceps for mitochondrial ATP output, Alpha GPC as a cholinergic precursor for acute focus. Acute performance window, not all-day stimulant load.
Cordyceps Energy Gummies
200mg Cordyceps · 30 gummies
Cordyceps militaris extract standardised for cordycepin content. Supports VO2 max and mitochondrial efficiency — clean, sustained energy without the cortisol spike of caffeine.
Ashwagandha Plus KSM-66
600mg KSM-66 · 60 capsules
KSM-66 standardised to 5% withanolides — the exact specification used in the Chandrasekhar et al. trial. Daytime adaptogenic stamina; modulates the stress response without sedation.

RENEW

The cellular foundation.

RENEW addresses the cellular foundation that REST and RISE build on. NAD+ levels decline by roughly 50% between your 20s and 50s. The RENEW stack approaches that decline from two angles simultaneously.

NAD+ Capsules
500mg NAD+ · 60 capsules
Direct NAD+ supplementation supports the coenzyme that drives sirtuin activity and mitochondrial energy production. Pairs with NMN for biosynthetic precursor coverage.
NMN Capsules
500mg NMN · 99.9% purity
Nicotinamide Mononucleotide as a direct NAD+ precursor. 99.9% pharmaceutical-grade purity, identity-tested by HPLC. Supports the salvage pathway that maintains cellular NAD+ pools.

05 · HOW WE MAKE IT

Manufactured without shortcuts. Tested without exceptions.

Every AE·ORA product is manufactured in a 21 CFR Part 111 GMP-compliant facility in the United States. GMP compliance is a floor, not a ceiling.

HPLC laboratory testing environment

US MANUFACTURING

21 CFR Part 111 GMP Certified Facility

FDA mandatory Good Manufacturing Practice standard for dietary supplements. Full documentation at every stage from raw material receipt to finished product release. US-based facility. Every unit made here.

INDEPENDENT TESTING

Third-Party Verified. Every Batch.

Not internal QC. Not the manufacturer’s in-house lab. An independent third-party laboratory, every batch, before any unit ships. Not spot checks, not quarterly audits. Every batch. Certificate of Analysis on file and available on request.

POTENCY STANDARD

±5% of Label Dose

HPLC testing against authenticated reference standards. Our specification is ±5% of label dose. The dietary supplement industry standard is ±20%. We set our own. If the label says 275mg elemental magnesium, the capsule contains 275mg.

FULL PANEL TESTING

Heavy Metals. Microbial. Identity. Potency.

Every batch tested for identity, potency, heavy metals (full panel — arsenic, cadmium, lead, mercury), and microbial contamination to USP standards. COA documenting lot number, test date, and results. Available on request. Always.

06 · THE INVITATION

Check our work. Then try it.

We publish the dose rationale for every ingredient. We link the trials. We list every supplier specification. We make the COAs available. We want you to verify everything before you buy. That is not confidence. It is accountability.

  • Peer-reviewed dose anchoring
  • GMP certified US manufacturing
  • Third-party tested every batch
  • No proprietary blends
  • COA on request
  • Free US shipping over $75